Globally, more than half of patients die after infection with the neglected tropical disease, melioidosis, often before they are diagnosed. A new rapid test could save lives by diagnosing patients in hours, rather than several days taken by current bacterial culture methods, meaning they receive the correct antibiotics faster. The test uses CRISPR to detect […]
People with essential tremor (ET) have nearly three times increased risk of developing dementia compared with the general population, new research showed. In a prospective, longitudinal study, incidence of dementia was nearly 20% among older adults with ET. However, the rates were lower than those in adults with Parkinson’s disease. The study is “the most […]
A recent study in the journal Cancer investigates the association between metabolic syndrome (MetS) score trajectories and cancer risks using a large-scale prospective cohort. Study: The association of metabolic syndrome scores trajectory patterns with risk of all cancer types. Image Credit: Sebastian Kaulitzki / Shutterstock.com How does MetS impact health? MetS is associated with multiple conditions that co-occur […]
President Joe Biden on Saturday signed into law a measure that softened – but did not completely eliminate – a 2024 cut in a key rate used to determine how physicians are paid for treating Medicare patients. While physician groups hailed the move as partial relief, they say they’ll continue to press for broader changes […]
New study indicates that mushroom extract might demonstrate superior efficacy compared to chemically synthesized psilocybin, especially in stimulating neuroplasticity and promoting the development of new connections between nerve cells—an essential attribute. This discovery unveils potential applications for addressing conditions such as depression, PTSD, and schizophrenia. A new study led by Orr Shahar, a PhD student, […]
SAN DIEGO — In published trials, both an IL-17 inhibitor and an IL-23 inhibitor achieved impressive rates of clear or almost clear responses in patients with moderate to severe plaque psoriasis, but late-breaker data presented at the annual American Academy of Dermatology meeting show that these types of responses are sustained for as long as […]
The body’s inability to produce enough insulin or use it effectively often results in type 2 diabetes (T2D), a chronic disease affecting hundreds of millions of people around the globe. Disease management is crucial to avoid negative long-term outcomes, such as limb amputation or heart disease. To counteract adverse consequences, it is crucial that patients […]
SAN DIEGO — New guidelines for cutaneous melanoma have been issued by the National Comprehensive Cancer Network (NCCN), creating some new standards of practice that extend a slow divergence from the last set of detailed recommendations released by the American Academy of Dermatology (AAD) in 2019. Based on the constantly evolving science that drives guidelines, […]
Helicases are enzymes that unwind DNA and RNA. They’re central to cellular life, implicated in a number of cancers and infections-;and, alas, extraordinarily difficult to target with drugs. Now, new research provides a powerful platform for designing covalent inhibitors tailored to target helicases. The paper, published in the Journal of the American Chemical Society, describes how researchers […]
Disappointing phase 3 trial results of a drug approved for the treatment of amyotrophic lateral sclerosis (ALS) may prompt the manufacturer to voluntarily pull it from the market, the company announced today. After 48 weeks, sodium phenylbutyrate-taurursodiol (Relyvrio) offered no significant improvements compared to placebo, failing to meet the randomized controlled trial’s primary or secondary […]