In a recent review published in the journal PNAS, researchers explore non-viral and cell-specific clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated proteins (Cas) delivery methods and emphasize their advantages for research and gene therapy applications. Study: Targeted nonviral delivery of genome editors in vivo. Image Credit: Catalin Rusnac / Shutterstock.com Improving the delivery of CRISPR-Cas enzymes CRISPR-Cas […]
WEST PALM BEACH, FLORIDA — When evaluated at 3 or 12 months, serum neurofilament light chain (sNfL) levels were predictive of new or enlarging T2 lesions in patients with multiple sclerosis (MS) regardless of treatment assignment, new sub-study data from the ASCLEPIOS I/II trials showed. The findings were presented at the 2024 Americas Committee for […]
More than 70% of American Indian young adults aged 20-39 and 50% of American Indian teens have cholesterol levels or elevated fat in the blood that put them at risk for cardiovascular disease, suggests a study supported by the National Institutes of Health. In some cases, these levels -; specifically high low-density lipoprotein (LDL) cholesterol, […]
The US Food and Drug Administration (FDA) has cleared Dexcom’s Stelo Glucose Biosensor System as the first over-the-counter continuous glucose monitoring (CGM) system. Unlike Dexcom’s G6 and G7 CGM systems, the Stelo is intended for adults with or without diabetes who don’t use insulin. “Importantly, this system is not for individuals with problematic hypoglycemia as […]
For years, scientists have expressed concern about potential adverse health effects of excessive exposure to short wavelength light (SWL), which includes the “blue light” from smartphones, laptops, and tablets. However, the International Commission on Non-Ionizing Radiation Protection (ICNIRP) has identified a lack of consensus among public health officials about whether SWL from artificial sources disrupts […]
An app developed by researchers at the University of Bristol assesses the risk of sudden unexpected death in infancy (SUDI) Baby Sleep Planner app. Credit: University of Bristol and improves the communication of safer sleep advice to families. Following positive appraisals from professionals and families, it could soon be rolled out more widely. The rate […]
The total number of children, adolescents and adults worldwide living with obesity has surpassed one billion, according to a global analysis published in The Lancet. These trends, together with the declining prevalence of people who are underweight since 1990, make obesity the most common form of malnutrition across the majority of countries worldwide. The new […]
The US Food and Drug Administration (FDA) has approved Boston Scientific’s Agent Drug-Coated Balloon (DCB), the first coronary DCB for the treatment of coronary in-stent restenosis in patients with coronary artery disease, the company has announced in a news release. In-stent restenosis makes up an estimated 10% of percutaneous coronary interventions in the United States. […]
Mendelian randomization, a powerful tool in medical research, helps us understand whether certain factors truly cause disease. This technique uses genetic variations as “natural experiments” to reveal cause-and-effect relationships. However, choosing the proper genetic variations is crucial for accurate results. Think of a train network where the genetic variation is the starting point, the exposure […]
Imagine a world where Sherlock Holmes has the sharpest mind but no intriguing mysteries to solve. Or Iron Man without his tech-suit. They are simply incomplete without one another. In the same way, lead generation is the lifeline of businesses. Without a consistent inflow of customers, even the best business idea will fail to flourish. […]