A cell-free DNA (cfDNA) blood test, aimed at detecting abnormal DNA signals in people with an average risk of colorectal cancer (CRC), correctly detected CRC in most people confirmed to have the disease, according to a new study. The cfDNA blood test had 83% sensitivity for CRC, 90% specificity for advanced neoplasia, and 13% sensitivity […]
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For the first time, researchers at the University of Minnesota Twin Cities showed that non-invasive brain stimulation can change a specific brain mechanism that is directly related to human behavior. This is a major step forward for discovering new therapies to treat brain disorders such as schizophrenia, depression, Alzheimer’s disease, and Parkinson’s disease. The study […]
As US medical school graduates learned Friday, March 15, where they would spend their residencies, new Match Day 2024 data showed a loss of interest in pediatrics, whereas emergency medicine regained popularity after concern over last year’s unfilled positions. Hospitals and medical groups offered 41,503 residency positions in 2024, a 3% increase from last year, […]
In a review published in BMC Medicine, researchers examined the current literature to investigate malaria vaccination’s challenges in reaching high-risk children and discussed the policy implications. They identified health system-related risks that could hinder malaria vaccine effectiveness and proposed solutions to ensure equitable and universal protection against the disease. Study: Malaria vaccination: hurdles to reach high-risk […]
The US Food and Drug Administration (FDA) has approved tislelizumab-jsgr (Tevimbra, BeiGene, Ltd.) as second-line monotherapy for certain adult patients with unresectable or metastatic esophageal squamous cell carcinoma (ESCC). Specifically, the novel checkpoint inhibitor is approved for patients with ESCC after prior systemic chemotherapy that did not include a programmed death–ligand 1 (PD-L1) inhibitor. Approval […]
Globally, more than half of patients die after infection with the neglected tropical disease, melioidosis, often before they are diagnosed. A new rapid test could save lives by diagnosing patients in hours, rather than several days taken by current bacterial culture methods, meaning they receive the correct antibiotics faster. The test uses CRISPR to detect […]
People with essential tremor (ET) have nearly three times increased risk of developing dementia compared with the general population, new research showed. In a prospective, longitudinal study, incidence of dementia was nearly 20% among older adults with ET. However, the rates were lower than those in adults with Parkinson’s disease. The study is “the most […]
A recent study in the journal Cancer investigates the association between metabolic syndrome (MetS) score trajectories and cancer risks using a large-scale prospective cohort. Study: The association of metabolic syndrome scores trajectory patterns with risk of all cancer types. Image Credit: Sebastian Kaulitzki / Shutterstock.com How does MetS impact health? MetS is associated with multiple conditions that co-occur […]
President Joe Biden on Saturday signed into law a measure that softened – but did not completely eliminate – a 2024 cut in a key rate used to determine how physicians are paid for treating Medicare patients. While physician groups hailed the move as partial relief, they say they’ll continue to press for broader changes […]
New study indicates that mushroom extract might demonstrate superior efficacy compared to chemically synthesized psilocybin, especially in stimulating neuroplasticity and promoting the development of new connections between nerve cells—an essential attribute. This discovery unveils potential applications for addressing conditions such as depression, PTSD, and schizophrenia. A new study led by Orr Shahar, a PhD student, […]