Author Archives: admin

Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs. Details on the findings, which were reported in the September 7 issue of Nature Structural & Molecular Biology [DOI: 10.1038/s41594-023-01085-6], could lead to the development of […]

TOPLINE: Nonalcoholic fatty liver disease (NAFLD) is an independent risk factor for precancerous colorectal adenomatous polyps in men and women, according to results of a large study. METHODOLOGY: Researchers conducted a retrospective review of the medical records of adults who underwent abdominal ultrasound and colonoscopy at a single hospital in China from January 2018 to […]

In a recent study published in PLOS Digital Health, researchers investigated the complexity of polypharmacy and whether frequent dose adjustments were required for co-medications and drug pairs in hospital settings. Study: Study explores association between polypharmacy and dose adjustments. Image Credit:solarseven/Shutterstock.com Polypharmacy, a growing concern in healthcare due to multimorbid, aging populations, increases the risk […]

AMSTERDAM — A short course of the interleukin-1 receptor antagonist, anakinra, appeared safe but did not reduce complications of acute myocarditis in the ARAMIS trial. The trial was presented at the European Society of Cardiology (ESC) Congress 2023 held recently in Amsterdam, the Netherlands. Lead investigator, Mathieu Kerneis, MD, Pitie Salpetriere APHP University Hospital, Paris, […]

In a recent review published in Cell, a group of authors delved into the complexities of menopause, assessed its global impacts on health, and evaluated the effectiveness and safety of current treatments, emphasizing the importance of further research. Study: Menopause—Biology, consequences, supportive care, and therapeutic options. Image Credit: AlesiaKan/Shutterstock.com Background Menopause, commonly experienced by women […]

Artificial intelligence voice assistants (VAs) programmed to guide bystanders performing cardiopulmonary resuscitation (CPR) for patients in cardiac arrest can offer unrelated or inaccurate advice, new research suggests. Investigators studied four widely used voice assistants, as well as ChatGPT, to determine their ability to provide assistance to bystanders seeking to provide CPR. They found that nearly […]

In a recent study posted to the bioRxiv preprint* server, researchers in Sweden investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein amyloid as a potential triggering factor for protein misfolding and amyloid formation in neurodegenerative diseases (NDs). Neurodegenerative diseases such as Creutzfeldt-Jakob disease (CJD) and Alzheimer’s disease (AD) are accelerated by the […]

The European Society of Cardiology has released new guidelines for cardiomyopathies, their first major comprehensive international guidelines to address diagnosis and treatment of the broad causes of heart muscle dysfunction. The document was released in conjunction with the European Society of Cardiology (ESC) Congress 2023 and is now available online in the European Heart Journal. […]

Aging reduces metabolism and clearance, which leads to an increase in oxidative and inflammatory stress in the body. An individual’s quality of life, including diet and exercise, plays a crucial role in the prevention of age-related diseases. Marine resources contain unique glycerophospholipid plasmalogens and various valuable nutrients that could be beneficial for the prevention of […]

AMSTERDAM — Dropping aspirin and using low-dose prasugrel (Effient) alone in the initial month of treatment after percutaneous coronary intervention (PCI) failed to lower bleeding risk compared with dual antiplatelet therapy (DAPT), and there was a signal of possible harm in terms of increased subacute stent thrombosis, in the STOPDAPT-3 trial. “Therefore, dual antiplatelet therapy […]