Author Archives: admin

A new trial testing perioperative treatment with colchicine has shown no significant benefit on the co-primary outcomes of clinically important atrial fibrillation (AF) or myocardial injury after noncardiac surgery (MINS) in patients undergoing thoracic surgery. Trends were seen with reductions in events, but these did not reach significance. However, benefit was seen in a post […]

A new editorial paper was published in Oncoscience (Volume 10) on August 17, 2023, entitled, “Cancer drug development yesterday, today and tomorrow.” In this new editorial, researchers Elzbieta Izbicka and Robert T. Streeper from New Frontier Labs discuss the history of cancer drug development and how it has evolved over time. The editorial also highlights […]

TOPLINE: The indirect and direct costs of alcohol-associated liver disease (ALD) could sap the US economy of $880 billion from 2022 to 2040, a new analysis shows. METHODOLOGY: Researchers estimated the current and projected economic burden of direct healthcare spending, productivity loss, and premature mortality due to ALD in the US population. They used a […]

Beginning as far back as ten years before even being diagnosed, women with endometriosis utilise the healthcare system more than women without this chronic illness. Research sheds new light on widespread delays in diagnosis. Endometriosis is a chronic – often painful – illness that only affects women. New research shows potential for shortening the path […]

TOPLINE: Social and environmental factors drive race and ethnicity-associated gut microbiome variation that arise around 3 months of age, which may contribute to adult health and health disparities, new research shows. METHODOLOGY: Researchers analyzed data from eight cohort studies with 2756 gut microbiome samples from 729 children of diverse race/ethnic backgrounds from birth to 12 […]

In a recent systematic review published in BMC Neurology, researchers examined recent studies exploring neuroimaging modalities aided by advanced machine learning (ML) algorithms that predicted Alzheimer’s disease (AD) progression from mild cognitive impairment (MCI) to AD dementia. MCI is the early stage of AD when a patient is symptomatic, but full-fledged AD dementia has not set in.  […]

The woman arrived for her first therapy session distressed and depressed. Her husband of 20 years had just announced that he was in love with someone else. At 47, she was so upset she had a heart attack and then needed to go on disability from work.  “She had her sense of self shaken at […]

Hepatocellular carcinoma (HCC) is the most commonly diagnosed cancer of the liver and the fourth leading cause of cancer-related mortality worldwide, with China accounting for over half of the global annual cases and deaths. Hepatectomy is the standard curative-intent treatment option for appropriately selected patients with localized HCC. However, the high postoperative recurrence rate causes […]

TOPLINE: The oncolytic viral immunotherapy talimogene laherparepvec (T-VEC; Imlygic) was associated with a significant improvement in 5-year survival outcomes, including overall survival, compared with surgery alone in patients with advanced resectable melanoma, new data suggest. METHODOLOGY: This phase 2, open-label randomized clinical trial enrolled 150 patients with resectable stage IIIB to IVM1a melanoma and one […]

One of the hallmarks of Alzheimer’s disease is disruption to the body’s circadian rhythm, the internal biological clock that regulates many of our physiological processes. Nearly 80% of people with Alzheimer’s experience these issues, including difficulty sleeping and worsening cognitive function at night. However, there are no existing treatments for Alzheimer’s that target this aspect […]