Small molecules called immunomodulators can help create more effective vaccines and stronger immunotherapies to treat cancer. But finding the molecules that instigate the right immune response is difficult -;the number of drug-like small molecules has been estimated to be 1060, much higher than the number of stars in the visible universe. In a potential first […]

Women with bipolar disorder were three times more likely than were healthy controls to experience polycystic ovarian syndrome, based on data from nearly 250 individuals. Previous studies suggest that the prevalence of polycystic ovarian syndrome (PCOS) is higher in bipolar disorder (BD) patients compared with individuals not diagnosed with BD, wrote Jieyu Liu, PhD, of […]

Glaucoma is one of the leading causes of blindness worldwide, and vision loss, due to the loss of retinal ganglion cells (RGCs), cannot currently be reversed with any treatment. Some studies have looked at replacing RGCs through cell transplants, but this process is still in the research and development stage and fraught with limitations that […]

TOPLINE: An international expert consensus offers guidance to diagnose, assess, and treat adult patients experiencing drug reaction with eosinophilia and systemic symptoms (DRESS). METHODOLOGY: Data on the evaluation, assessment, and treatment of the rare but potentially life-threatening drug hypersensitivity reaction are lacking. To support clinicians in diagnosing and managing DRESS, a steering committee conducted a […]

Infants prenatally exposed to cannabis are more likely to be born preterm, have a low birth weight, and require neonatal intensive care unit (NICU) care than infants without prenatal cannabis exposure, according to a study published today in the scientific journal Addiction. However, cannabis-exposed infants are not at greater risk of birth defects or death […]

Sit less, move more. Or stand more. Or sleep more. Replacing 30 minutes of sitting a day with equal time standing or even sleeping could improve obesity markers like body weight and waist circumference, according to a new cross-sectional study investigating the impact of movement behavior on cardiometabolic health.  The findings suggest that, while higher-intensity […]

In a recent study published in Communications Biology, researchers investigated how spouses influence each other’s sleep patterns and circadian preferences, using data from large-scale studies, including the United Kingdom (UK) Biobank and 23andMe.  Study: Correlations in sleeping patterns and circadian preference between spouses. Image Credit: Gorodenkoff/Shutterstock.com Background  Insufficient and disturbed sleep, including insomnia and short sleep […]

Artificial intelligence can distinguish overlapping inflammatory conditions with total accuracy, according to a new study presented (abstract 2040) on November 14 at the 2023 annual meeting of the American College of Rheumatology. Texas pediatricians faced a conundrum during the pandemic. Endemic typhus, a flea-borne tropical infection common to the region, is nearly indistinguishable from multisystem […]

University of Queensland research has shown a link between parental stress stemming from financial hardship and exacerbated asthma symptoms in children. Dr K M Shahunja from UQ’s Poche Centre for Indigenous Health led a study that analyzed the data of more than 3,900 children collected over 14 years in the Longitudinal Study of Australian Children. […]

ANAHEIM, California — A specially formulated toothpaste (INT301, Intrommune Therapeutics) met its safety endpoints as an oral immunotherapy to help adults with peanut allergy reduce their reaction risk, according to findings of a phase 1 study. The 48-week, randomized, double-blind, placebo-controlled trial enrolled 32 adults aged 18–55 with peanut allergy to receive in a 3:1 […]