In a recent article published in Nutrients, researchers evaluated associations of breast cancer incidence with different dietary phosphate levels. Study: High Dietary Phosphorus Is Associated with Increased Breast Cancer Risk in a U.S. Cohort of Middle-Aged Women. Image Credit: Rembolle/Shutterstock.com They hypothesized that the lowest level of phosphate (P) intake (800–1000 mg) per the National Kidney […]

AMSTERDAM — Systematic screening by primary care physicians for cardiovascular disease (CVD) in high-risk adults — those with type 2 diabetes, chronic obstructive pulmonary disease (COPD), or both — more than doubled the rate of incident CVD diagnosed compared with usual care in a Dutch study involving more than 1200 people and 25 primary care […]

In a recent study published in the Journal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+/Δ), the most common genetic alteration in clonal hematopoiesis (CH), contribute to colitis-associated colon cancer (CAC) pathogenesis. Study: Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer. Image Credit: vetpathologist/Shutterstock.com Background CH, the clonal expansion of mutant […]

Computer-assisted colonoscopy driven by artificial intelligence (AI) may increase detection of small polyps, but not colorectal neoplasias or advanced adenomas, two new reports show. A multicenter, parallel, randomized controlled trial in Spain of patients with a positive fecal immunochemical test (FIT) found that use of AI was not associated with better detection of advanced neoplasias. […]

In a recent study posted to the preprint* server Research Square while under review for publication in BMC Medical Genomics, researchers investigate the potential causal relationship between gastroesophageal reflux disease (GERD) and the risk of heavy menstrual bleeding (HMB) during regular menstrual cycles. Study: A causal association between gastroesophageal reflux disease and risk of heavy menstrual bleeding […]

A new trial testing perioperative treatment with colchicine has shown no significant benefit on the co-primary outcomes of clinically important atrial fibrillation (AF) or myocardial injury after noncardiac surgery (MINS) in patients undergoing thoracic surgery. Trends were seen with reductions in events, but these did not reach significance. However, benefit was seen in a post […]

A new editorial paper was published in Oncoscience (Volume 10) on August 17, 2023, entitled, “Cancer drug development yesterday, today and tomorrow.” In this new editorial, researchers Elzbieta Izbicka and Robert T. Streeper from New Frontier Labs discuss the history of cancer drug development and how it has evolved over time. The editorial also highlights […]

TOPLINE: The indirect and direct costs of alcohol-associated liver disease (ALD) could sap the US economy of $880 billion from 2022 to 2040, a new analysis shows. METHODOLOGY: Researchers estimated the current and projected economic burden of direct healthcare spending, productivity loss, and premature mortality due to ALD in the US population. They used a […]

Beginning as far back as ten years before even being diagnosed, women with endometriosis utilise the healthcare system more than women without this chronic illness. Research sheds new light on widespread delays in diagnosis. Endometriosis is a chronic – often painful – illness that only affects women. New research shows potential for shortening the path […]

TOPLINE: Social and environmental factors drive race and ethnicity-associated gut microbiome variation that arise around 3 months of age, which may contribute to adult health and health disparities, new research shows. METHODOLOGY: Researchers analyzed data from eight cohort studies with 2756 gut microbiome samples from 729 children of diverse race/ethnic backgrounds from birth to 12 […]