In a recent systematic review published in BMC Neurology, researchers examined recent studies exploring neuroimaging modalities aided by advanced machine learning (ML) algorithms that predicted Alzheimer’s disease (AD) progression from mild cognitive impairment (MCI) to AD dementia. MCI is the early stage of AD when a patient is symptomatic, but full-fledged AD dementia has not set in.  […]

The woman arrived for her first therapy session distressed and depressed. Her husband of 20 years had just announced that he was in love with someone else. At 47, she was so upset she had a heart attack and then needed to go on disability from work.  “She had her sense of self shaken at […]

Hepatocellular carcinoma (HCC) is the most commonly diagnosed cancer of the liver and the fourth leading cause of cancer-related mortality worldwide, with China accounting for over half of the global annual cases and deaths. Hepatectomy is the standard curative-intent treatment option for appropriately selected patients with localized HCC. However, the high postoperative recurrence rate causes […]

TOPLINE: The oncolytic viral immunotherapy talimogene laherparepvec (T-VEC; Imlygic) was associated with a significant improvement in 5-year survival outcomes, including overall survival, compared with surgery alone in patients with advanced resectable melanoma, new data suggest. METHODOLOGY: This phase 2, open-label randomized clinical trial enrolled 150 patients with resectable stage IIIB to IVM1a melanoma and one […]

One of the hallmarks of Alzheimer’s disease is disruption to the body’s circadian rhythm, the internal biological clock that regulates many of our physiological processes. Nearly 80% of people with Alzheimer’s experience these issues, including difficulty sleeping and worsening cognitive function at night. However, there are no existing treatments for Alzheimer’s that target this aspect […]

TOPLINE: Patients with Parkinson’s disease (PD) whose caregivers have depression are more likely to have worse quality of life and more emergency department visits than those whose caregivers don’t have depression, results of a new study suggest. METHODOLOGY: Research shows that caregiver burden is correlated with greater motor symptoms, cognitive impairment, and disrupted sleep among people with […]

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd-;but very important-;to help them fight pathogens and destroy cancer cells. This receptor, called retinoic acid receptor alpha (RARα), is known to control gene expression programs in the nucleus, but it also now appears to operate outside the […]

TOPLINE: A new study shows that extreme heat is associated with suicidality among incarcerated men, a finding that may have implications for legal interventions and advocacy to reduce heat-induced morbidity and mortality in prisons. METHODOLOGY: Extreme heat poses a distinct risk to incarcerated people, many of whom have high rates of behavioral health conditions and are held […]

Severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, according to a small study funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. These changes may help explain why the disease can damage so many different organs and […]

Are your Facebook Ads strategy ready for Black Friday?  This is THE time of the year when shopaholics are hunting for the best offers, so you need to make sure your Facebook Ads and Instagram Ads campaigns are ready to attract hungry buyers.  So, do you have your Black Friday Facebook Ads strategies all planned […]