In a recent retrospective study published in Scientific Reports, researchers from China investigated the effectiveness of low-dose aspirin (LDA) in reducing adverse pregnancy outcomes in the special case of twins conceived via assisted reproductive technology (ART). They found that while LDA could effectively preclude preeclampsia (PE) without a significant bleeding risk, it could not prevent […]
Cancer Research UK-funded scientists have made an unusual discovery that could help to identify patients who are up to two and a half times more likely to respond to currently available cancer drugs. Scientists at the Cancer Research UK Scotland Institute and Memorial Sloan Kettering Cancer Centre in the USA have “rewired” the DNA of […]
For patients with high-risk prostate cancer, treatment with long-term androgen deprivation therapy (ADT) and high-dose radiation was associated with significantly better progression-free, cancer-specific, and overall survival compared with ADT and standard-dose radiation. The investigators also found that the patients taking long-term ADT and high-dose radiation did not experience additional late urinary tract or gastrointestinal toxicities. […]
An international academic consortium has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes. The analysis, conducted by 23 experts from 11 countries, was led by The Johns Hopkins University in the United States, the Chinese University of Hong Kong in Hong Kong, and […]
TOPLINE: The vaccine Cervarix was effective in protecting women from cervical cancer when administered between ages 12 and 13 years, according to a new study published in Journal of the National Cancer Institute. METHODOLOGY: Cervical cancer is the fourth most common cancer among women worldwide. Programs to provide Cervarix, a bivalent vaccine, began in the […]
Non-alcoholic fatty liver disease (NAFLD), recently renamed metabolic dysfunction-associated fatty liver disease (MAFLD), is spectrum of diseases that ranges from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH). Invasive liver biopsy continues to be the gold standard for diagnosing NASH through the histopathological assessment of liver steatosis, ballooning and lobular inflammation. However, this method does […]
TOPLINE: Significant associations were found between readmission with diabetic ketoacidosis (DKA) in people with type 1 diabetes (T1D) and both substance abuse and incarceration. METHODOLOGY: At a large county hospital in Texas, an electronic health records query for patients with T1D admitted with a DKA diagnosis between 2019 and 2021 identified 243 with at least […]
The Icahn School of Medicine at Mount Sinai has been awarded a grant of more than $4 million from The Leona M. and Harry B. Helmsley Charitable Trust to support an innovative research project aimed at understanding the early stages of Crohn’s disease before noticeable symptoms develop. Led by the Department of Genetics and Genomic […]
The United States has a maternal mortality crisis. In 2021, 1205 women in this country died of pregnancy-related causes, up from 861 in 2020. Meanwhile, an estimated 80% of these deaths are preventable. Some experts say follow-up care in the year after delivery is critical to monitor for any complications, and primary care clinicians play […]
A European consortium of 19 partners has been awarded over €6.5M by the European Union to study psilocybin to treat psychological distress in people with progressive incurable illnesses requiring palliative care. This is the first time the EU has funded a multi-site clinical study into psychedelic-assisted therapy. The randomized controlled trial (RCT) PsyPal, coordinated by […]