In a recent study published in NEJM, researchers conducted a phase III clinical trial to test the effectiveness of three repurposed drugs – metformin, ivermectin, and fluvoxamine, in preventing progression to severe coronavirus disease 2019 (COVID-19). Study: Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19. Image Credit: Robert Coolen/Shutterstock Background Current vaccines and inpatient […]
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Mothers who have a family history of any psychiatric disorder have almost two times the risk of postpartum depression as do mothers without such history, according to a new study. Mette-Marie Zacher Kjeldsen, MSc, with the National Center for Register-based Research at Aarhus (Denmark) University, led the study, a meta-analysis that included 26 studies with […]
Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Hebrew University in Jerusalem have identified in mice the cell of origin of combined liver/biliary duct carcinomas, a rare type of cancer of the liver. The pro-inflammatory immune messenger interleukin 6 (IL-6) was found to be the driver of carcinogenesis. Blocking of IL-6 […]
Having a million-dollar marketing funnel is nothing to scoff at. It’s a huge accomplishment that deserves its’ kudos. There’s a lot of automation, dedication, and ideation that goes into making something like that happen. It’s the type of benchmark that says, “Hey, I was a serious business owner at 6-figures. But now? I turned my […]
BUENOS AIRES, Argentina — Vaccinating against monkeypox can complement other public health measures aimed at containing the current outbreak in nonendemic countries. However, when it comes to the need to immunize now, we need to “calm down,” according to officials and experts at a meeting organized by Argentina’s Ministry of Health. Another issue to be […]
Zhengzheng Shi and colleagues at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan report the effects of a common herbal remedy on colitis, one of two conditions that comprise inflammatory bowel disease (IBD). Published in Frontiers in Immunology, the study shows that DKT—a standard formula containing ginger, pepper, ginseng, and maltose—reduced the severity […]
Discontinuing stable, long-term opioid therapy may not be necessary for patients who show no signs of misuse – and it could even be safer than tapering or abrupt discontinuation, new research suggests. Investigators analyzed data for almost 200,000 patients who did not have signs of opioid use disorder (OUD) and were receiving opioid treatment. The […]
Bone health requires a balanced activity of various bone cell types including bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoporosis occurs when osteoclasts dominate without adequate bone formation to compensate. In new research published in the Journal of Bone and Mineral Research, elevated blood levels of a certain chemokine, or small signaling protein, that promotes osteoclast formation […]
What to Do About Polio Polio is back in the United States. The first case of paralytic polio was reported last month in New York, and the disease has also been found in the city’s wastewater. Only 1 in 4 people infected with poliovirus are symptomatic, and less than 1% of patients develop paralysis, so […]
New research published today by the University of Southampton shows new insight into how our brain develops, that can pave the way for treating neurological disorders. For the first time, a team of international scientists led by the University’s Professor of Neuroimmunology, Diego Gomez-Nicola, have studied the development of the main immune cell population residing […]